Fmoc Lys(AMCA)-OH

Unit Size
Price (USD)
Cat.#: 1682-100
Unit size: 100 mg
in stock
Cat.#: 1682-500
Unit size: 500 mg
in stock
Cat.#: 1682-1G
Unit size: 1000 mg
in stock
Cat.#: 1682-5G
Unit size: 5 g
in stock

AMCA (7-amino-4-methyl-3-coumarinacetic acid) is a blue fluorescent dye that is a non-sulfonated version of the Alexa Fluor® 350 dye. It is often used as a contrasting probe for double -  and triple - labeling in immunofluorescence microscopy, arrays, and in situ hybridization. The desirable properties of AMCA dyes include a relatively large Stoke’s shift and resistance to photobleaching.

Fmoc Lys(AMCA) OH is a building block for in-sequence peptide labeling by AMCA dye. It allows incorporation of fluorescent tag into a peptide chain using standard Fmoc peptide solid phase synthesis. This reagent is supplied as Boc protected derivative to ensure compatibility with Fmoc solid phase peptide synthesis. Spacers of different lengths are available upon request.

Primary amines
Abs/Em Maxima
345/450 nm
Extinction coefficient
19,000 cm-1M-1
Spectrally similar dyes
Alexa Fluor® 350, AMCA, DyLight® 350
Molecular weight
Storage conditions
Shipping conditions
Ambient temperature