• Sign In
  • No products in the cart.

AFDye 488 DBCO

Catalog#: 1021-1
Unit size: 1 mg
In stock
Catalog#: 1021-5
Unit size: 5 mg
In stock
Catalog#: 1021-25
Unit size: 25 mg
In stock
Catalog#: 1021-100
Unit size: 100 mg
In stock

AFDye™ 488 DBCO (Alexa Fluor® 488 DIBO analog) reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, AFDye™ 488 DBCO is an ideal alternative to copper requiring fluorescent alkynes.

AFDye™ 488 is a bright, highly photostable, green-fluorescent probe optimally excited by the 488 nm laser line. This probe is water-soluble and its fluorescence is pH independent over a wide pH range. The brightness and photostability of AFDye™ 488 is best suited to direct imaging of low-abundance targets.

AFDye™ 488 dye is structurally identical to Alexa Fluor® 488 sold by Thermo Fisher Scientific.

Abs/Em Maxima
494/517 nm
Extinction coefficient
73,000 cm-1M-1
Water, DMSO, DMF
Spectrally similar dyes
Alexa Fluor® 488, DyLight® 488, Fluorescein, Oregon Green 488
Molecular weight
Storage conditions
Shipping conditions
Ambient temperature

Alexa Fluor® is a registered trademark of Invitrogen, part of Thermo Fisher Scientific. Fluoroprobes is not affiliated with or endorsed by Thermo Fisher Scientific. AFDyes™ are GENERIC versions of Alexa Fluor® Dyes and ARE NOT manufactured, distributed, or affiliated in any way with Thermo Fisher Scientific.