5-TAMRA Cadaverine

Catalog#: 1261-5
Unit size: 5 mg
$79.00
In stock
Catalog#: 1261-25
Unit size: 25 mg
$195.00
In stock
Catalog#: 1261-100
Unit size: 100 mg
$495.00
In stock
Catalog#: 1261-1000
Unit size: 1000 mg
$1,895.00
In stock

5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).

Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.

Reactivity
Primary amine
Abs/Em Maxima
553/575 nm
Extinction coefficient
91,000 cm-1M-1
Solubility
DMSO, DMF, MeOH
Spectrally similar dyes
Alexa Fluor® 546, TAMRA, CF™ 543, MB™ 543
Molecular weight
627.24 (TFA salt)
Storage conditions
-20C
Shipping conditions
Ambient temperature